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Retatrutide360

Retatrutide Brand Name (and Why "Reta," "GLP-3" and "Triple G" Exist)

There is no retatrutide brand name yet. See every name it goes by, from LY3437943 to reta and GLP-3, and when Lilly's brand is likely to appear after filing.

JPWritten by Juan Pablo FríasMedically reviewed by Dr. Juan Pablo FríasUpdated October 31, 202623 sources5 min read

There is no retatrutide brand name yet. As of October 2026, Eli Lilly still calls the drug retatrutide, its generic name, and its only other official name is the development code LY3437943. Lilly last said it plans to file with the FDA in the first quarter of 2027, and its recent brands, like Zepbound and Foundayo, were each announced in an approval release. Reta, GLP-3 and triple G are nicknames, and labels like R-10 or GLP-3 Reta belong to sellers of unapproved vials.

Nonebrand names announced by Lilly, as of October 2026
LY3437943Lilly's code for retatrutide, used alone in its Phase 2 trial
Q1 2027Lilly's last stated plan for an FDA filing (Sep 29, 2026)
90 daysFDA's goal for reviewing a brand name sent with an NDA or BLA

Key takeaways

  • Retatrutide is the generic name, and it's the only official name besides Lilly's code LY3437943.
  • Reta, GLP-3 and triple G are nicknames. R-10, R-20 and GLP-3 Reta are labels on unapproved vials, not Lilly products.
  • Tirzepatide's two brands, Mounjaro and Zepbound, and orforglipron's Foundayo were each announced in Lilly's approval release. Lilly's last stated plan for retatrutide is an FDA filing in Q1 2027.
  • Retatrutide is not Zepbound or Mounjaro. Those are tirzepatide, which has no glucagon action; retatrutide adds it.
  • The WHO's February 2026 list of naming endings includes -trutide, for peptides that act on the GLP-1, glucagon and GIP receptors.

Why there's no retatrutide brand name yet

A drug picks up its names in layers: the company's code, then an official generic name, then a brand chosen for the market. Retatrutide has reached the second layer and stopped, because nothing has been approved to sell. Lilly's FAQ, updated in October 2026, says "Retatrutide is an investigational medicine that is not on the market." It adds that the drug "has not been reviewed or approved by the FDA or any regulatory agency in the world."

The registry shows both layers. Lilly's Phase 2 obesity trial (NCT04881760) is titled "A Study of LY3437943", with no generic name, while the Phase 3 TRIUMPH-1 record reads "Retatrutide (LY3437943)". That's why the 2022 Cell Metabolism discovery paper uses the code and later papers use the name.

Every name retatrutide goes by

These are the names we found as of October 2026, with a primary source for each where one exists.

NameWhat it isWhere it comes from
RetatrutideGeneric (nonproprietary) nameLilly releases, ClinicalTrials.gov
LY3437943 (LY-3437943)Lilly's development codePhase 2 registry record, the 2022 Cell Metabolism discovery paper
UNII NOP2Y096GV, CAS 2381089-83-2Registry identifiers for the moleculeFDA Global Substance Registration System
RetaNickname, and a label on unapproved vialsVictoria Department of Health alert, 2026
R-10, R-20Labels on unapproved vialsVictoria Department of Health alert, 2026
GLP-3Media nicknameLilly FAQ calls it scientifically inaccurate
"GLP-3 Reta (Retatrutide)"A seller's product nameFDA warning letter, August 24, 2026
"GLP-1-R peptide"A seller's product name for retatrutideFDA warning letter, March 31, 2026
Triple GInformal shorthand for GIP, GLP-1 and glucagonNo primary source uses it

None of these is a brand. A brand name is a trademark the maker registers and the FDA reviews, and Lilly hasn't announced one.

Is retatrutide the same as Zepbound or Mounjaro?

No. Mounjaro and Zepbound are both tirzepatide, Lilly's GIP and GLP-1 drug, sold under one name for type 2 diabetes and another for weight. Retatrutide is a separate molecule that adds a third target, the glucagon receptor. Foundayo is orforglipron, a pill. Our retatrutide vs Zepbound and retatrutide vs Mounjaro pages compare the trial results, and retatrutide vs tirzepatide compares the molecules.

What the name retatrutide means

The ending does the work. Under the World Health Organization's naming system, -tide marks a peptide, and the WHO's February 2026 list of candidate endings includes -trutide, for blood-sugar-lowering peptides that act on three receptors at once, GLP-1, glucagon and GIP. Retatrutide carries that ending, and tirzepatide, a two-receptor drug, doesn't.

The chemical name is long. The FDA's substance record spells out 39 amino acids, three of them non-standard, with a 20-carbon fatty acid chain attached at position 17. Our retatrutide structure page walks through it, and how to pronounce retatrutide covers saying it.

Where reta, GLP-3 and triple G come from

Reta is a clipped version of the name, the way people say "tirz" for tirzepatide. GLP-3 and triple G both count receptors: semaglutide works on one, tirzepatide on two and retatrutide on three.

Which hormone receptors each drug acts on

Retatrutide adds glucagon to the two receptors tirzepatide already targets

DrugGIPGLP-1Glucagon
SemaglutideOzempic, WegovyNoYesNo
TirzepatideMounjaro, ZepboundYesYesNo
RetatrutideInvestigationalYesYesYes
Sources: Coskun et al., Cell Metabolism, 2022; Zepbound (tirzepatide) prescribing information; Wegovy (semaglutide) prescribing information.

None of those receptors is called GLP-3. Lilly's FAQ calls the nickname a scientifically inaccurate label used informally in the media, and prefers "triple agonist". Our GLP-3 guide has the full story, and how retatrutide works explains what the third receptor adds.

When will retatrutide get a brand name?

Nobody outside Lilly knows, but the FDA process and Lilly's launches narrow it down. Under FDA guidance from 2016, a company can ask the agency to review a proposed brand name no earlier than the end of Phase 2. The FDA then checks it for look-alike or sound-alike confusion with other drug names, a known cause of medication errors. The review goal is 90 days for a name sent in with a marketing application (an NDA or BLA), against 180 days for one sent earlier, while the drug is still in trials.

The filing route is in dispute, but the name clock doesn't depend on it. Lilly last said, on September 29, 2026, that it plans to submit retatrutide to the FDA in the first quarter of 2027 as a Biologics License Application (BLA). On October 2, 2026, the FDA decided that retatrutide is a drug, not a biological product, so an application would need to be filed under section 505 of the Federal Food, Drug, and Cosmetic Act. Lilly's appeal on that question is pending in the Seventh Circuit, and we found no ruling as of October 31, 2026. Our FDA approval and release date pages follow what happens next.

MoleculeDevelopment codeBrandApproval announced
TirzepatideLY3298176Mounjaro (type 2 diabetes)May 13, 2022
TirzepatideLY3298176Zepbound (weight)November 8, 2023
OrforglipronLY3502970Foundayo (weight)April 1, 2026
RetatrutideLY3437943Not announcedNone; Lilly's last stated plan is a filing in Q1 2027

Dates are those of Lilly's approval releases. Tirzepatide's two brands came about 18 months apart; Lilly hasn't said whether retatrutide will split the same way.

Our read: if retatrutide follows those three launches, its brand name will go public with FDA approval, which can't come until after a filing and a full review. Until Lilly announces a name, any retatrutide "brand" on a vial or website is a seller's label.

Names on vials sold online

Lilly's October 28, 2026 release says retatrutide "cannot be legally sold or marketed for human use", so any name on a vial bought online is the seller's invention. In a September 14, 2026 safety alert, Australia's TGA said a vial sold as retatrutide contained no retatrutide at all. The TGA's lab found undeclared semaglutide at about 8 times the level in approved semaglutide products. If you're weighing what people list as retatrutide for sale, start from that fact rather than the label. Our legality guide covers the rules by country.

The only legal way to get real retatrutide is through Lilly's retatrutide program, meaning its trials or a narrow expanded access route. Our clinical trials guide covers how to find one, and searching "retatrutide" or "LY3437943" on ClinicalTrials.gov shows what's open.

Frequently asked questions

What is the brand name for retatrutide?

It doesn't have one yet. Lilly still calls the drug retatrutide, its generic name. It last said, on September 29, 2026, that it plans to file with the FDA in the first quarter of 2027, and its recent brands, like Zepbound and Foundayo, were announced in the approval releases. So the name may not go public until around approval.

Is retatrutide the same as Zepbound or Mounjaro?

No. Zepbound and Mounjaro are brand names for tirzepatide, which acts on the GIP and GLP-1 receptors. Retatrutide is a different molecule that adds the glucagon receptor, and it has no brand and no approval. Both are Lilly drugs.

What is another name for retatrutide?

The only other official name is LY3437943, the code Eli Lilly used for it in early studies. People online call it reta, GLP-3 or triple G, but those are nicknames, and none of them is a brand.

What is reta peptide called?

Reta is short for retatrutide. Vials sold online carry labels like Reta, R-10, R-20 or GLP-3 Reta, but those are seller names. No approved retatrutide product exists anywhere.

What is the chemical name for retatrutide?

Its full systematic name in the FDA's substance registry runs to about 490 characters because it spells out all 39 amino acids plus an attached fatty acid chain. For lookups, the same record lists CAS number 2381089-83-2 and UNII NOP2Y096GV.

Is retatrutide available in other countries under a different name?

No. Retatrutide isn't approved in any country, so it has no brand anywhere, and Lilly's multinational trials use the same name and code, retatrutide (LY3437943). The UK's MHRA, Australia's TGA and Health Canada have all warned about products sold as retatrutide outside trials.

Sources

  1. Lilly's triple agonist, retatrutide, successful in two additional Phase 3 obesity trials, delivering significant improvements in weight and A1C. Eli Lilly and Company (PR Newswire), 2026. prnewswire.com
  2. FDA approves Lilly's Zepbound (tirzepatide) for chronic weight management. Eli Lilly and Company (PR Newswire), 2023. prnewswire.com
  3. FDA approves Lilly's Foundayo (orforglipron), the only GLP-1 pill for weight loss that can be taken any time of day without food or water restrictions. Eli Lilly and Company (PR Newswire), 2026. prnewswire.com
  4. Lilly's retatrutide delivered greater A1C reduction and more than double the weight loss of Ozempic's highest approved dose in head-to-head trial. Eli Lilly and Company (PR Newswire), 2026. prnewswire.com
  5. Lilly's triple agonist, retatrutide, delivered substantial weight loss and A1C reduction, underscoring its potential promise for people with obesity and type 2 diabetes. Eli Lilly and Company (PR Newswire), 2026. prnewswire.com
  6. FDA remand decision on retatrutide, October 2, 2026 (Eli Lilly v. Kennedy, 7th Cir. No. 26-1301, Doc. 46-2). U.S. Food and Drug Administration (filed in the U.S. Court of Appeals for the Seventh Circuit), 2026. storage.courtlistener.com
  7. Eli Lilly and Company v. Robert Kennedy Jr. (docket). CourtListener, 2026. courtlistener.com
  8. What to know about retatrutide. Eli Lilly and Company, 2026. lilly.com
  9. A Study of LY3437943 in Participants Who Have Obesity or Are Overweight (NCT04881760). ClinicalTrials.gov, 2026. clinicaltrials.gov
  10. A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight (TRIUMPH-1, NCT05929066). ClinicalTrials.gov, 2026. clinicaltrials.gov
  11. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. Cell Metabolism, 2022. doi.org
  12. Retatrutide substance record (UNII NOP2Y096GV). U.S. Food and Drug Administration, Global Substance Registration System, 2026. precision.fda.gov
  13. Toxicity linked to unapproved peptide product labelled Retatrutide. Victoria Department of Health, 2026. health.vic.gov.au
  14. Warning letter to Peptide Partners LLC (MARCS-CMS 735063). U.S. Food and Drug Administration, 2026. fda.gov
  15. Warning letter to Gram Peptides (MARCS-CMS 721806). U.S. Food and Drug Administration, 2026. fda.gov
  16. Pre-stems: Suffixes used in the selection of INN, February 2026 (INN Working Document 25.628). World Health Organization, 2026. who.int
  17. Contents of a Complete Submission for the Evaluation of Proprietary Names: Guidance for Industry. U.S. Food and Drug Administration, 2016. fda.gov
  18. A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight (SURMOUNT-1, NCT04184622). ClinicalTrials.gov, 2026. clinicaltrials.gov
  19. FDA approves Lilly's Mounjaro (tirzepatide) injection, the first and only GIP and GLP-1 receptor agonist for the treatment of adults with type 2 diabetes. Eli Lilly and Company (PR Newswire), 2022. prnewswire.com
  20. A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-1, NCT05869903). ClinicalTrials.gov, 2026. clinicaltrials.gov
  21. TGA tests counterfeit retatrutide product following serious adverse event report. Therapeutic Goods Administration (Australia), 2026. tga.gov.au
  22. MHRA smashes major illicit weight loss medicine production facility in record seizure. Medicines and Healthcare products Regulatory Agency (UK), 2025. gov.uk
  23. Think twice before injecting peptides bought online: unauthorized products can seriously harm you (RA-81874). Health Canada, 2026. recalls-rappels.canada.ca
JPF
Author & Medical ReviewerVerified Physician Reviewer

Dr. Juan Pablo Frías, MD

Physician-Scientist & Clinical Trialist • Endocrinology, Diabetes & Metabolism

Dr. Frías earned his M.D. from Vanderbilt University School of Medicine and completed his endocrinology fellowship at UC San Diego. A principal investigator on landmark incretin trials (including retatrutide, tirzepatide and semaglutide), he reviews all guides on Retatrutide360 for clinical accuracy, dosing safety and evidence fidelity.

Medical disclaimer. Retatrutide is an investigational medicine and no approved version exists yet. This page is educational, not medical advice. Talk to a doctor before starting, changing or stopping any medication, and get urgent care for severe symptoms.